Nyob rau hauv siab -kev ntim tshuaj thiab kev kho mob kom zoo nkauj, tsis muaj kev cuam tshuam yog tus yuam sij rau kev tswj xyuas cov khoom siv thiab cov khoom noj kom raug. Txawm hais tias koj tab tom sau siab -viscosity dermal fillers, kho hniav gels, los yog cov txheej txheem ncua kev kawm nyuaj, txhaws hauv txoj kev txhaws yog ib qho kev ntxhov siab tshaj plaws uas pab pawg tsim khoom tuaj yeem ntsib.
Lub taub hau lossis lub twj tso kua mis tsis yog txwv tsis pub ntau lawm; nws tuaj yeem ua rau lub siab tsim-ups, lub cev muaj zog overloads, cov khoom shear degradation, thiab cov khoom kim heev pov tseg.
Txhawm rau pab koj pab pawg engineering thiab kev saib xyuas kom muaj lub sijhawm ua haujlwm siab tshaj plaws, ntawm no yog cov lus qhia siv tau los txheeb xyuas, daws teeb meem, thiab tiv thaiv cov teeb meem clogging hauv kojsyringe filling khoom.
Kauj Ruam 1: Kev txheeb xyuas lub hauv paus ua rau (Qhov Clog nyob qhov twg?)
Ua ntej dismantling koj cov kab filling, koj yuav tsum cais qhov chaw ntawm kev txwv. Feem ntau cov blockages nyob rau hauv ib tug automated syringe muab tub lim tshwm sim nyob rau hauv ib qho ntawm peb qhov chaw tseem ceeb:
| Clog qhov chaw | Cov tsos mob tseem ceeb | Common culprits |
| Rotary Piston / Ceramic Twj | Lub cev muaj zog torque tswb, sib tsoo suab nrov, los yog ua tiav qaug dab peg ntawm lub twj tso kua mis tsav. | Cov khoom siv crystallization, cov khoom sib xyaw ua ke, lossis cov twj tso kua mis tsis raug- rau - lub tes tsho clearance kam rau ua. |
| Filling Nozzle / Koob Qhia | "Dripping" tom qab kaw-tawm, tailing, tsis sib npaug ntawm qhov hnyav, lossis ua tiav qhov txhaws ntawm qhov ncauj. | Cov khoom ziab tawm thaum nres ib ntus, micro- npuas nthuav dav, lossis tsis raug nozzle geometry. |
| Cov kua dej pub Tubes / Manifold | Lub siab spikes nyob rau hauv cov kab noj, qeeb priming, los yog erratic flow rates. | Kub poob ua rau gel solidification, los yog cov khoom sedimentation nyob rau hauv kev ncua. |
Theem 2: Kauj Ruam -los ntawm -Txoj kev daws teeb meem raws tu qauv
Thaum muaj teeb meem tshwm sim, ua raws li cov txheej txheem txheej txheem txheej txheem no kom daws tau qhov teeb meem yam tsis muaj kev puas tsuaj rau siab -qhov kev sib cuag qhov tseeb:
Kauj Ruam 1: Tshawb xyuas qhov kub thiab txias viscosity
Ntau lub siab -viscosity gels (xws li hyaluronic acid) tso siab rau kev tswj qhov kub thiab txias kom tswj tau qhov dej kom zoo.
Kev Ua: Xyuas kom tseeb tias lub tsho cua sov ntawm koj lub hopper thiab cov khoom manifold ua haujlwm raug. Ib qho poob ntawm 2℃mus rau 3℃tuaj yeem ua rau qee cov gels thicken sai, ua rau txhaws.
Kauj Ruam 2: Ua kom qis -Npaj kua dej ntws tawm
Tsis txhob sim tam sim ntawd tshem tawm qhov txhaws nozzle los ntawm kev quab yuam siab pneumatic los ntawm lub kaw lus, vim qhov no tuaj yeem ua rau lub raj tawg lossis puas lub twj tso kua mis me me.
Qhov Kev Ua: Hloov lub tshuab mus rau hom phau ntawv, thim rov qab lub nozzles, thiab sim ua kom qeeb, qis - siab ntws los siv cov kuab tshuaj sov uas tsis muaj menyuam lossis cov dej distilled. Qhov no muaj kev nyab xeeb dissolves los yog dislodges ib ntus crystallization.
Kauj Ruam 3: Tshawb xyuas Ceramic Pump Clearance
Kev kho mob-qib cov twj tso kua mis ceramic yog tsim los nrog kev ceev nrawm heev (feem ntau ntsuas hauv microns) kom ua tiav qhov kev txhaj tshuaj ntau yam tsis muaj cov ntsaws ruaj ruaj. Txawm li cas los, qhov no ua rau lawv rhiab heev rau particulate kev sib txhuam.
Kev Ua: Ua tib zoo disassemble lub twj tso kua mis sib dhos hauv qab aseptic. Tshawb xyuas lub cev khawb lossis "galling" ntawm lub plunger ceramic. Ntxuav lub rooj sib txoos hauv lub da dej ultrasonic kom tshem tawm cov micro-cov khoom xyaw crystallized.
Kauj Ruam 4: Tshawb xyuas Nozzle Tip thiab Tshuab -Cov Chaw Rov Qab
Yog hais tias qhov clog tshwm sim ntau zaus ntawm qhov kawg ntawm rab koob, qhov teeb meem zoo li "qhuav" thaum lub sij hawm luv luv, lossis tsis raug txhua yam teeb tsa.
Kev Ua: Txheeb xyuas HMI tshuab-rov qab (suck{1}}rov qab) nqis. Yog tias qhov nqus- rov qab siab lossis qhov deb tau hloov kho siab dhau lawm, nws rub cov huab cua huv hauv chav rau hauv lub taub hau, ziab tawm cov qauv thiab tsim cov ntsaws ruaj ruaj. Kho lub tshuab- rov qab tsis tau mus rau qhov tsawg kawg nkaus uas yuav tsum tau ua kom tsis txhob ntog.
Theem 3: Cov Tswv Yim Zoo los tiv thaiv yav tom ntej Clogging
Tus nqi tshaj - txoj hauv kev zoo los daws cov khoom siv tshuaj tua kab mob yog tiv thaiv kom tsis txhob muaj qhov tshwm sim thawj zaug. Siab - cov tshuab ua haujlwm zoo thiab kev ua haujlwm ntse ua haujlwm yog koj qhov kev tiv thaiv zoo tshaj plaws:
1. Kev nqis peev hauv "Tuag-Zone-Dawb" Txoj Kev Dej Hiav Txwv
Kev sib txuas ntawm cov kua dej ib txwm siv nrog cov ntse 90℃khoov lossis cov xov sab hauv tsim cov chaw nyob ruaj khov uas cov ntaub ntawv tuaj yeem sib sau ua ke, qhuav tawm, thiab thaum kawg tawg los ua ib qho thaiv.
Kev Tiv Thaiv Kev Tsim: Ua kom koj cov cuab yeej ua haujlwm zoo, zoo heev polished 316L stainless hlau manifold nrog tri-clamp kev sib txuas. Txoj kev tuag -zone- txoj kev pub dawb ua kom cov dej nrawm nrawm nrawm.
2. Siv Automated ntub dej-Cap thiab "Nozzle Bath" nta
Thaum ib txoj kab raug ncua rau tus neeg teb xov tooj tawg lossis cov qauv hloov pauv, cov txheej txheem uas raug rau chav dej laminar ntws yuav sai sai rau ntawm lub taub hau nozzle.
Kev Tiv Thaiv Kev Tsim Kho: Cov tshuaj tua kab mob siab tshaj plaws tuaj yeem teeb tsa nrog kev siv lub tshuab ntub dej -cap lossis ntu ntu micro- faib ua haujlwm. Thaum lub sijhawm nres, lub kaw lus cia li kaw lub taub hau lub taub hau hauv qhov chaw ntub dej lossis ua haujlwm me me, ntu ntu kom tshem tawm cov kua dej ua haujlwm.
3. Standardize Intensive CIP/SIP Cycles
Sij hawm dhau mus, microscopic organic residues tuaj yeem tsim nyob rau ntawm phab ntsa sab hauv ntawm cov hlab ntsha thiab cov twj tso kua mis, nqaim txoj hauv kev ntws.
Kev Tiv Thaiv Kev Tsim Kho: Tsim kom muaj kev huv huv huv- hauv -Place (CIP) raws tu qauv tam sim tom qab txhua qhov kev khiav haujlwm. Tsis txhob cia siab -viscosity gels lossis suspensions zaum hauv lub tshuab thaum hmo ntuj.
Xaus: Koom tes rau Kev Txhim Kho Cov Dej Dynamics
Clogging tsis tshua muaj tsuas yog "mechanical" tsis ua haujlwm-nws yog ib qho tsos mob ntawm cov dej tsis sib haum, qhov kub thiab txias, thiab lub tshuab teeb tsa. Kev kov yeej cov kev cov nyom no yuav tsum tau siv lub tshuab syringe muab tub lim tsim los tswj cov khoom siv lub cev tshwj xeeb ntawm koj cov kev tsim tshwj xeeb.
NtawmTXOJ KEV, peb tsim pebua ntej- puv tshuab nqus tsev vacuum filling thiab stoppering tshuabnrog optimized, siab -kua kua txoj kev. Los ntawm kev cai-cov twj tso kua mis ceramic rau rhuab manifold kev sib koom ua ke, peb cov tshuab tau tsim los ua cov ntaub ntawv muaj kuab heev thiab rhiab heev nrog xoom clogging thiab lub sijhawm ua haujlwm siab tshaj plaws.
Puas yog koj tab tom ntsib teeb meem ntau lawm?Hu raucov kws tshaj lij engineering ntawm ALWELL hnub no. Xa koj cov ntaub ntawv tsis pub dhau peb, thiab cia peb pab neeg tsim kho kom haum, txhaws -dawb filling tov rau koj qhov chaw.